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A mechanism for S-adenosyl methionine assisted formation of a riboswitch conformation: a small molecule with a strong arm
The S-adenosylmethionine-1 (SAM-I) riboswitch mediates expression of proteins involved in sulfur metabolism via formation of alternative conformations in response to binding by SAM. Models for kinetic trapping of the RNA in the bound conformation require annealing of nonadjacent mRNA segments during...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770654/ https://www.ncbi.nlm.nih.gov/pubmed/19720737 http://dx.doi.org/10.1093/nar/gkp664 |