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A mechanism for S-adenosyl methionine assisted formation of a riboswitch conformation: a small molecule with a strong arm

The S-adenosylmethionine-1 (SAM-I) riboswitch mediates expression of proteins involved in sulfur metabolism via formation of alternative conformations in response to binding by SAM. Models for kinetic trapping of the RNA in the bound conformation require annealing of nonadjacent mRNA segments during...

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Detalles Bibliográficos
Autores principales:	Huang, Wei, Kim, Joohyun, Jha, Shantenu, Aboul-ela, Fareed
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770654/ https://www.ncbi.nlm.nih.gov/pubmed/19720737 http://dx.doi.org/10.1093/nar/gkp664

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