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ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice
Expansion of a tandem repeat tract is responsible for the Repeat Expansion diseases, a group of more than 20 human genetic disorders that includes those like Fragile X (FX) syndrome that result from repeat expansion in the FMR1 gene. We have previously shown that the ATM and Rad3-related (ATR) check...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770655/ https://www.ncbi.nlm.nih.gov/pubmed/19710035 http://dx.doi.org/10.1093/nar/gkp666 |