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Argonaute2 Suppresses Drosophila Fragile X Expression Preventing Neurogenesis and Oogenesis Defects

Fragile X Syndrome is caused by the silencing of the Fragile X Mental Retardation gene (FMR1). Regulating dosage of FMR1 levels is critical for proper development and function of the nervous system and germ line, but the pathways responsible for maintaining normal expression levels are less clearly...

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Detalles Bibliográficos
Autores principales: Pepper, Anita S.-R., Beerman, Rebecca W., Bhogal, Balpreet, Jongens, Thomas A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770736/
https://www.ncbi.nlm.nih.gov/pubmed/19888420
http://dx.doi.org/10.1371/journal.pone.0007618