Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

The transcription factor SOX9 regulates cartilage extracellular matrix gene expression and is essential for chondrocyte differentiation. We previously showed that activation of p38 MAPK by cycloheximide in human chondrocytes leads to stabilization of SOX9 mRNA (Tew SR and Hardingham TE. J Biol Chem...

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Detalles Bibliográficos
Autores principales: Tew, Simon R., Peffers, Mandy J., McKay, Tristan R., Lowe, Emma T., Khan, Wasim S., Hardingham, Timothy E., Clegg, Peter D.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2009
Materias:
Receptors and Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770738/
https://www.ncbi.nlm.nih.gov/pubmed/19657054
http://dx.doi.org/10.1152/ajpcell.00571.2008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770738/
https://www.ncbi.nlm.nih.gov/pubmed/19657054
http://dx.doi.org/10.1152/ajpcell.00571.2008

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