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The Antitumor Effect and Hepatotoxicity of a Hexokinase II Inhibitor 3-Bromopyruvate: In Vivo Investigation of Intraarterial Administration in a Rabbit VX2 Hepatoma Model

OBJECTIVE: The purpose of this study was to compare the antitumor effect and hepatotoxicity of an intraarterial delivery of low-dose and high-dose 3-bromopyruvate (3-BrPA) and those of a conventional Lipiodol-doxorubicin emulsion in a rabbit VX2 hepatoma model. MATERIALS AND METHODS: This experiment...

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Detalles Bibliográficos
Autores principales: Jae, Hwan Jun, Chung, Jin Wook, Park, Hee Sun, Lee, Min Jong, Lee, Ki Chang, Kim, Hyo-Cheol, Yoon, Jung Hwan, Chung, Hesson, Park, Jae Hyung
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770822/
https://www.ncbi.nlm.nih.gov/pubmed/19885316
http://dx.doi.org/10.3348/kjr.2009.10.6.596