Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells

Remodelling of mitochondrial metabolism is a hallmark of cancer. Mutations in the genes encoding succinate dehydrogenase (SDH), a key Krebs cycle component, are associated with hereditary predisposition to pheochromocytoma and paraganglioma, through mechanisms which are largely unknown. Recently, th...

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Detalles Bibliográficos
Autores principales: Cervera, Ana M, Bayley, Jean-Pierre, Devilee, Peter, McCreath, Kenneth J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770992/
https://www.ncbi.nlm.nih.gov/pubmed/19849834
http://dx.doi.org/10.1186/1476-4598-8-89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770992/
https://www.ncbi.nlm.nih.gov/pubmed/19849834
http://dx.doi.org/10.1186/1476-4598-8-89

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