Cargando…

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase

BACKGROUND: The 18 residue tail abutting the SH3 fold that comprises the heart of the C-terminal domain is the only part of HIV-1 integrase yet to be visualized by structural biology. To ascertain the role of the tail region in integrase function and HIV-1 replication, a set of deletion mutants that...

Descripción completa

Detalles Bibliográficos
Autores principales: Dar, Mohd J, Monel, Blandine, Krishnan, Lavanya, Shun, Ming-Chieh, Di Nunzio, Francesca, Helland, Dag E, Engelman, Alan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770994/
https://www.ncbi.nlm.nih.gov/pubmed/19840380
http://dx.doi.org/10.1186/1742-4690-6-94