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Lgl2 Executes Its Function as a Tumor Suppressor by Regulating ErbB Signaling in the Zebrafish Epidermis

Changes in tissue homeostasis, acquisition of invasive cell characteristics, and tumor formation can often be linked to the loss of epithelial cell polarity. In carcinogenesis, the grade of neoplasia correlates with impaired cell polarity. In Drosophila, lethal giant larvae (lgl), discs large (dlg),...

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Detalles Bibliográficos
Autores principales: Reischauer, Sven, Levesque, Mitchell P., Nüsslein-Volhard, Christiane, Sonawane, Mahendra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771016/
https://www.ncbi.nlm.nih.gov/pubmed/19911055
http://dx.doi.org/10.1371/journal.pgen.1000720