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Selection for Genetic Variation Inducing Pro-Inflammatory Responses under Adverse Environmental Conditions in a Ghanaian Population

BACKGROUND: Chronic inflammation is involved in the pathogenesis of chronic age-associated, degenerative diseases. Pro-inflammatory host responses that are deleterious later in life may originate from evolutionary selection for genetic variation mediating resistance to infectious diseases under adve...

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Detalles Bibliográficos
Autores principales: Kuningas, Maris, May, Linda, Tamm, Riin, van Bodegom, David, van den Biggelaar, Anita H. J., Meij, Johannes J., Frölich, Marijke, Ziem, Juventus B., Suchiman, Helena E. D., Metspalu, Andres, Slagboom, P. Eline, Westendorp, Rudi G. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771352/
https://www.ncbi.nlm.nih.gov/pubmed/19907653
http://dx.doi.org/10.1371/journal.pone.0007795