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Selection for Genetic Variation Inducing Pro-Inflammatory Responses under Adverse Environmental Conditions in a Ghanaian Population
BACKGROUND: Chronic inflammation is involved in the pathogenesis of chronic age-associated, degenerative diseases. Pro-inflammatory host responses that are deleterious later in life may originate from evolutionary selection for genetic variation mediating resistance to infectious diseases under adve...
Autores principales: | Kuningas, Maris, May, Linda, Tamm, Riin, van Bodegom, David, van den Biggelaar, Anita H. J., Meij, Johannes J., Frölich, Marijke, Ziem, Juventus B., Suchiman, Helena E. D., Metspalu, Andres, Slagboom, P. Eline, Westendorp, Rudi G. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771352/ https://www.ncbi.nlm.nih.gov/pubmed/19907653 http://dx.doi.org/10.1371/journal.pone.0007795 |
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