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Tumor-Like Stem Cells Derived from Human Keloid Are Governed by the Inflammatory Niche Driven by IL-17/IL-6 Axis

BACKGROUND: Alterations in the stem cell niche are likely to contribute to tumorigenesis; however, the concept of niche promoted benign tumor growth remains to be explored. Here we use keloid, an exuberant fibroproliferative dermal growth unique to human skin, as a model to characterize benign tumor...

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Detalles Bibliográficos
Autores principales: Zhang, Qunzhou, Yamaza, Takayoshi, Kelly, A. Paul, Shi, Shihong, Wang, Songlin, Brown, Jimmy, Wang, Lina, French, Samuel W., Shi, Songtao, Le, Anh D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771422/
https://www.ncbi.nlm.nih.gov/pubmed/19907660
http://dx.doi.org/10.1371/journal.pone.0007798