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A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 Ubc9

Phosphorylation and SUMO conjugation contribute to the spatial and temporal regulation of substrates containing phosphorylation-dependent SUMO consensus motifs (PDSM). MEF2 is a transcription factor and PDSM substrate whose modification by SUMO drives postsynaptic dendritic differentiation. NMR anal...

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Detalles Bibliográficos
Autores principales: Mohideen, Firaz, Capili, Allan D., Bilimoria, Parizad M., Yamada, Tomoko, Bonni, Azad, Lima, Christopher D.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771680/
https://www.ncbi.nlm.nih.gov/pubmed/19684601
http://dx.doi.org/10.1038/nsmb.1648