Dual and opposing roles of primary cilia in medulloblastoma development

Recent work has shown that primary cilia are essential for Hh signaling during mammalian development1–9. It is also known that aberrant Hedgehog (Hh) signaling can lead to cancer10, but the role of primary cilia in oncogenesis is not known. Cerebellar granule neuron precursors (GNPs) can give rise t...

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Detalles Bibliográficos
Autores principales: Han, Young-Goo, Kim, Hong Joo, Dlugosz, Andrzej A., Ellison, David W., Gilbertson, Richard J., Alvarez-Buylla, Arturo
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771737/
https://www.ncbi.nlm.nih.gov/pubmed/19701203
http://dx.doi.org/10.1038/nm.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771737/
https://www.ncbi.nlm.nih.gov/pubmed/19701203
http://dx.doi.org/10.1038/nm.2020

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