Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas

The telomeric repeat binding factor 2 (TRF2) plays a central role in the protection of chromosome ends by inhibiting telomeres from initiating a DNA damage cascade. TRF2 overexpression has been suggested to induce tumor development in the mouse, and TRF2 levels have been found increased in human tum...

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Detalles Bibliográficos
Autores principales: Begemann, Sebastian, Galimi, Francesco, Karlseder, Jan
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772070/
https://www.ncbi.nlm.nih.gov/pubmed/20046894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772070/
https://www.ncbi.nlm.nih.gov/pubmed/20046894

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