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HETEROTYPIC INTERACTIONS ENABLED BY POLARIZED NEUTROPHIL MICRODOMAINS MEDIATE THROMBO-INFLAMMATORY INJURY

Selectins and their ligands mediate leukocyte rolling allowing interactions with chemokines that lead to integrin activation and arrest. Here, we demonstrate that E-selectin is critical to induce a secondary wave of activating signals transduced specifically by E-selectin ligand-1, that induces pola...

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Detalles Bibliográficos
Autores principales: Hidalgo, Andrés, Chang, Jungshan, Jang, Jung-Eun, Peired, Anna J., Chiang, Elaine Y., Frenette, Paul S.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772164/
https://www.ncbi.nlm.nih.gov/pubmed/19305412
http://dx.doi.org/10.1038/nm.1939