Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies

Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly used in these bacteria include Clustered Regu...

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Detalles Bibliográficos
Autores principales: Comas, Iñaki, Homolka, Susanne, Niemann, Stefan, Gagneux, Sebastien
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772813/
https://www.ncbi.nlm.nih.gov/pubmed/19915672
http://dx.doi.org/10.1371/journal.pone.0007815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772813/
https://www.ncbi.nlm.nih.gov/pubmed/19915672
http://dx.doi.org/10.1371/journal.pone.0007815

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