Using Non-Homogeneous Models of Nucleotide Substitution to Identify Host Shift Events: Application to the Origin of the 1918 ‘Spanish’ Influenza Pandemic Virus

Nonhomogeneous Markov models of nucleotide substitution have received scant attention. Here we explore the possibility of using nonhomogeneous models to identify host shift nodes along phylogenetic trees of pathogens evolving in different hosts. It has been noticed that influenza viruses show marked...

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Detalles Bibliográficos
Autores principales: dos Reis, Mario, Hay, Alan J., Goldstein, Richard A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772961/
https://www.ncbi.nlm.nih.gov/pubmed/19787384
http://dx.doi.org/10.1007/s00239-009-9282-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772961/
https://www.ncbi.nlm.nih.gov/pubmed/19787384
http://dx.doi.org/10.1007/s00239-009-9282-x

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