Cargando…

Differential Role of Human Choline Kinase α and β Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment

BACKGROUND: The Kennedy pathway generates phosphocoline and phosphoethanolamine through its two branches. Choline Kinase (ChoK) is the first enzyme of the Kennedy branch of synthesis of phosphocholine, the major component of the plasma membrane. ChoK family of proteins is composed by ChoKα and ChoKβ...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallego-Ortega, David, Ramirez de Molina, Ana, Ramos, Maria Angeles, Valdes-Mora, Fatima, Barderas, Maria Gonzalez, Sarmentero-Estrada, Jacinto, Lacal, Juan Carlos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773002/
https://www.ncbi.nlm.nih.gov/pubmed/19915674
http://dx.doi.org/10.1371/journal.pone.0007819