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Differential Role of Human Choline Kinase α and β Enzymes in Lipid Metabolism: Implications in Cancer Onset and Treatment
BACKGROUND: The Kennedy pathway generates phosphocoline and phosphoethanolamine through its two branches. Choline Kinase (ChoK) is the first enzyme of the Kennedy branch of synthesis of phosphocholine, the major component of the plasma membrane. ChoK family of proteins is composed by ChoKα and ChoKβ...
Autores principales: | Gallego-Ortega, David, Ramirez de Molina, Ana, Ramos, Maria Angeles, Valdes-Mora, Fatima, Barderas, Maria Gonzalez, Sarmentero-Estrada, Jacinto, Lacal, Juan Carlos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773002/ https://www.ncbi.nlm.nih.gov/pubmed/19915674 http://dx.doi.org/10.1371/journal.pone.0007819 |
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