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Metabolite Profiling Uncovers Plasmid-Induced Cobalt Limitation under Methylotrophic Growth Conditions

BACKGROUND: The introduction and maintenance of plasmids in cells is often associated with a reduction of growth rate. The reason for this growth reduction is unclear in many cases. METHODOLOGY/PRINCIPAL FINDINGS: We observed a surprisingly large reduction in growth rate of about 50% of Methylobacte...

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Detalles Bibliográficos
Autores principales: Kiefer, Patrick, Buchhaupt, Markus, Christen, Philipp, Kaup, Björn, Schrader, Jens, Vorholt, Julia A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773004/
https://www.ncbi.nlm.nih.gov/pubmed/19915676
http://dx.doi.org/10.1371/journal.pone.0007831