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Species-Specific Differences in the Expression of the HNF1A, HNF1B and HNF4A Genes

BACKGROUND: The HNF1A, HNF1B and HNF4A genes are part of an autoregulatory network in mammalian pancreas, liver, kidney and gut. The layout of this network appears to be similar in rodents and humans, but inactivation of HNF1A, HNF1B or HNF4A genes in animal models cause divergent phenotypes to thos...

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Detalles Bibliográficos
Autores principales: Harries, Lorna W., Brown, James E., Gloyn, Anna L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773013/
https://www.ncbi.nlm.nih.gov/pubmed/19924231
http://dx.doi.org/10.1371/journal.pone.0007855