Common fragile sites are characterized by histone hypoacetylation

Common fragile sites (CFSs) represent large, highly unstable regions of the human genome. CFS sequences are sensitive to perturbation of replication; however, the molecular basis for the instability at CFSs is poorly understood. We hypothesized that a unique epigenetic pattern may underlie the unusu...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Yanwen, Lucas, Isabelle, Young, David J., Davis, Elizabeth M., Karrison, Theodore, Rest, Joshua S., Le Beau, Michelle M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773265/
https://www.ncbi.nlm.nih.gov/pubmed/19717471
http://dx.doi.org/10.1093/hmg/ddp410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773265/
https://www.ncbi.nlm.nih.gov/pubmed/19717471
http://dx.doi.org/10.1093/hmg/ddp410

Ejemplares similares