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Common fragile sites are characterized by histone hypoacetylation

Common fragile sites (CFSs) represent large, highly unstable regions of the human genome. CFS sequences are sensitive to perturbation of replication; however, the molecular basis for the instability at CFSs is poorly understood. We hypothesized that a unique epigenetic pattern may underlie the unusu...

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Detalles Bibliográficos
Autores principales:	Jiang, Yanwen, Lucas, Isabelle, Young, David J., Davis, Elizabeth M., Karrison, Theodore, Rest, Joshua S., Le Beau, Michelle M.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773265/ https://www.ncbi.nlm.nih.gov/pubmed/19717471 http://dx.doi.org/10.1093/hmg/ddp410

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