Targeted delivery of bleomycin to the brain using photo-chemical internalization of Clostridium perfringens epsilon prototoxin

Cells infiltrating into normal brain from malignant brain tumors are protected by the blood brain barrier (BBB) which prevents the delivery and limits the effects of anti-tumor agents. We have evaluated the ability of photochemical internalization (PCI) to limit the effects of an agent known to broa...

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Detalles Bibliográficos
Autores principales: Hirschberg, Henry, Zhang, Michelle J., Gach, H. Michael, Uzal, Francisco A., Peng, Qian, Sun, Chung-Ho, Chighvinadze, David, Madsen, Steen J.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Laboratory Investigation - Human/animal tissue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773371/
https://www.ncbi.nlm.nih.gov/pubmed/19506813
http://dx.doi.org/10.1007/s11060-009-9930-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773371/
https://www.ncbi.nlm.nih.gov/pubmed/19506813
http://dx.doi.org/10.1007/s11060-009-9930-4

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