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Regulatory Function of a Novel Population of Mouse Autoantigen-Specific Foxp3(−) Regulatory T Cells Depends on IFN-γ, NO, and Contact with Target Cells
BACKGROUND: Both naturally arising Foxp3(+) and antigen-induced Foxp3(−) regulatory T cells (Treg) play a critical role in regulating immune responses, as well as in preventing autoimmune diseases and graft rejection. It is known that antigen-specific Treg are more potent than polyclonal Treg in sup...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773411/ https://www.ncbi.nlm.nih.gov/pubmed/19924236 http://dx.doi.org/10.1371/journal.pone.0007863 |