An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis

Aerobic organisms have a tricarboxylic acid (TCA) cycle that is functionally distinct from those found in anaerobic organisms. Previous reports indicate that the aerobic pathogen Mycobacterium tuberculosis lacks detectable α-ketoglutarate (KG) dehydrogenase activity and drives a variant TCA cycle in...

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Detalles Bibliográficos
Autores principales: Baughn, Anthony D., Garforth, Scott J., Vilchèze, Catherine, Jacobs, William R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773412/
https://www.ncbi.nlm.nih.gov/pubmed/19936047
http://dx.doi.org/10.1371/journal.ppat.1000662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773412/
https://www.ncbi.nlm.nih.gov/pubmed/19936047
http://dx.doi.org/10.1371/journal.ppat.1000662

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