Cleavage of the SARS Coronavirus Spike Glycoprotein by Airway Proteases Enhances Virus Entry into Human Bronchial Epithelial Cells In Vitro

BACKGROUND: Entry of enveloped viruses into host cells requires the activation of viral envelope glycoproteins through cleavage by either intracellular or extracellular proteases. In order to gain insight into the molecular basis of protease cleavage and its impact on the efficiency of viral entry,...

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Detalles Bibliográficos
Autores principales: Kam, Yiu-Wing, Okumura, Yuushi, Kido, Hiroshi, Ng, Lisa F. P., Bruzzone, Roberto, Altmeyer, Ralf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773421/
https://www.ncbi.nlm.nih.gov/pubmed/19924243
http://dx.doi.org/10.1371/journal.pone.0007870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773421/
https://www.ncbi.nlm.nih.gov/pubmed/19924243
http://dx.doi.org/10.1371/journal.pone.0007870

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