Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection

To exploit contemporary sequencing technologies for targeted genetic analyses, we developed a hybridization enrichment strategy for DNA capture that uses PCR products as subgenomic traps. We applied this strategy to 115 kb of the human genome encompassing 47 genes implicated in cardiovascular diseas...

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Detalles Bibliográficos
Autores principales: Herman, Daniel S, Hovingh, G Kees, Iartchouk, Oleg, Rehm, Heidi L, Kucherlapati, Raju, Seidman, J G, Seidman, Christine E
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773433/
https://www.ncbi.nlm.nih.gov/pubmed/19543287
http://dx.doi.org/10.1038/nmeth.1343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773433/
https://www.ncbi.nlm.nih.gov/pubmed/19543287
http://dx.doi.org/10.1038/nmeth.1343

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