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Pharmacokinetics and biodistribution of Erufosine in nude mice - implications for combination with radiotherapy

BACKGROUND: Alkylphosphocholines represent promising antineoplastic drugs that induce cell death in tumor cells by primary interaction with the cell membrane. Recently we could show that a combination of radiotherapy with Erufosine, a paradigmatic intravenously applicable alkylphosphocholine, in vit...

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Detalles Bibliográficos
Autores principales: Henke, Guido, Lindner, Lars H, Vogeser, Michael, Eibl, Hans-Jörg, Wörner, Jürgen, Müller, Arndt C, Bamberg, Michael, Wachholz, Kirsten, Belka, Claus, Jendrossek, Verena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773776/
https://www.ncbi.nlm.nih.gov/pubmed/19852786
http://dx.doi.org/10.1186/1748-717X-4-46