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Attenuation of Age-Related Metabolic Dysfunction in Mice With a Targeted Disruption of the Cβ Subunit of Protein Kinase A

The cyclic adenosine monophosphate–dependent protein kinase A (PKA) pathway helps regulate both cell growth and division, and triglyceride storage and metabolism in response to nutrient status. Studies in yeast show that disruption of this pathway promotes longevity in a manner similar to caloric re...

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Detalles Bibliográficos
Autores principales: Enns, Linda C., Morton, John F., Mangalindan, Ruby Sue, McKnight, G. Stanley, Schwartz, Michael W., Kaeberlein, Matt R., Kennedy, Brian K., Rabinovitch, Peter S., Ladiges, Warren C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773816/
https://www.ncbi.nlm.nih.gov/pubmed/19776218
http://dx.doi.org/10.1093/gerona/glp133