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Attenuation of Age-Related Metabolic Dysfunction in Mice With a Targeted Disruption of the Cβ Subunit of Protein Kinase A
The cyclic adenosine monophosphate–dependent protein kinase A (PKA) pathway helps regulate both cell growth and division, and triglyceride storage and metabolism in response to nutrient status. Studies in yeast show that disruption of this pathway promotes longevity in a manner similar to caloric re...
Autores principales: | Enns, Linda C., Morton, John F., Mangalindan, Ruby Sue, McKnight, G. Stanley, Schwartz, Michael W., Kaeberlein, Matt R., Kennedy, Brian K., Rabinovitch, Peter S., Ladiges, Warren C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773816/ https://www.ncbi.nlm.nih.gov/pubmed/19776218 http://dx.doi.org/10.1093/gerona/glp133 |
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