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Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts

AIM: The multifunctional signal molecule calmodulin kinase II (CaMKII) has been associated with cardiac arrhythmogenesis under conditions where its activity is chronically elevated. Recent studies report that its activity is also acutely elevated during acidosis. We test a hypothesis implicating CaM...

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Detalles Bibliográficos
Autores principales: Pedersen, T H, Gurung, I S, Grace, A, Huang, C L-H
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774152/
https://www.ncbi.nlm.nih.gov/pubmed/19416122
http://dx.doi.org/10.1111/j.1748-1716.2009.01991.x