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Immune hierarchy among HIV-1 CD8(+) T cell epitopes delivered by dendritic cells depends on MHC-I binding irrespective of mode of loading and immunization in HLA-A*0201 mice

Recent human immunodeficiency virus type 1 (HIV-1) vaccination strategies aim at targeting a broad range of cytotoxic T lymphocyte (CTL) epitopes from different HIV-1 proteins by immunization with multiple CTL epitopes simultaneously. However, this may establish an immune hierarchical response, wher...

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Detalles Bibliográficos
Autores principales: KLOVERPRIS, HENRIK N, KARLSSON, INGRID, THORN, METTE, BUUS, SØREN, FOMSGAARD, ANDERS
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774155/
https://www.ncbi.nlm.nih.gov/pubmed/19845536
http://dx.doi.org/10.1111/j.1600-0463.2009.02544.x