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The Death Effector Domains of Caspase-8 Induce Terminal Differentiation

The differentiation and senescence programs of metazoans play key roles in regulating normal development and preventing aberrant cell proliferation, such as cancer. These programs are intimately associated with both the mitotic and apoptotic pathways. Caspase-8 is an apical apoptotic initiator that...

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Detalles Bibliográficos
Autores principales: Mielgo, Ainhoa, Torres, Vicente A., Schmid, Michael C., Graf, Ryon, Zeitlin, Samantha G., Lee, Pedro, Shields, David J., Barbero, Simone, Jamora, Colin, Stupack, Dwayne G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774162/
https://www.ncbi.nlm.nih.gov/pubmed/19924290
http://dx.doi.org/10.1371/journal.pone.0007879