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The Bacterial Defensin Resistance Protein MprF Consists of Separable Domains for Lipid Lysinylation and Antimicrobial Peptide Repulsion

Many bacterial pathogens achieve resistance to defensin-like cationic antimicrobial peptides (CAMPs) by the multiple peptide resistance factor (MprF) protein. MprF plays a crucial role in Staphylococcus aureus virulence and it is involved in resistance to the CAMP-like antibiotic daptomycin. MprF is...

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Detalles Bibliográficos
Autores principales: Ernst, Christoph M., Staubitz, Petra, Mishra, Nagendra N., Yang, Soo-Jin, Hornig, Gabriele, Kalbacher, Hubert, Bayer, Arnold S., Kraus, Dirk, Peschel, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774229/
https://www.ncbi.nlm.nih.gov/pubmed/19915718
http://dx.doi.org/10.1371/journal.ppat.1000660