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The Bacterial Defensin Resistance Protein MprF Consists of Separable Domains for Lipid Lysinylation and Antimicrobial Peptide Repulsion
Many bacterial pathogens achieve resistance to defensin-like cationic antimicrobial peptides (CAMPs) by the multiple peptide resistance factor (MprF) protein. MprF plays a crucial role in Staphylococcus aureus virulence and it is involved in resistance to the CAMP-like antibiotic daptomycin. MprF is...
Autores principales: | Ernst, Christoph M., Staubitz, Petra, Mishra, Nagendra N., Yang, Soo-Jin, Hornig, Gabriele, Kalbacher, Hubert, Bayer, Arnold S., Kraus, Dirk, Peschel, Andreas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774229/ https://www.ncbi.nlm.nih.gov/pubmed/19915718 http://dx.doi.org/10.1371/journal.ppat.1000660 |
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