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Misguided Transcriptional Elongation Causes Mixed Lineage Leukemia

Fusion proteins composed of the histone methyltransferase mixed-lineage leukemia (MLL) and a variety of unrelated fusion partners are highly leukemogenic. Despite their prevalence, particularly in pediatric acute leukemia, many molecular details of their transforming mechanism are unknown. Here, we...

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Detalles Bibliográficos
Autores principales:	Mueller, Dorothee, García-Cuéllar, María-Paz, Bach, Christian, Buhl, Sebastian, Maethner, Emanuel, Slany, Robert K.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774266/ https://www.ncbi.nlm.nih.gov/pubmed/19956800 http://dx.doi.org/10.1371/journal.pbio.1000249

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