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Longitudinal Evaluation of an N-Ethyl-N-Nitrosourea-Created Murine Model with Normal Pressure Hydrocephalus

BACKGROUND: Normal-pressure hydrocephalus (NPH) is a neurodegenerative disorder that usually occurs late in adult life. Clinically, the cardinal features include gait disturbances, urinary incontinence, and cognitive decline. METHODOLOGY/PRINCIPAL FINDINGS: Herein we report the characterization of a...

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Detalles Bibliográficos
Autores principales: Lee, Ming-Jen, Chang, Ching-Pang, Lee, Yi-Hsin, Wu, Yi-Chih, Tseng, Hsu-Wen, Tung, Yu-Ying, Wu, Min-Tzu, Chen, Yen-Hui, Kuo, Lu-Ting, Stephenson, Dennis, Hung, Shuen-Iu, Wu, Jer-Yuarn, Chang, Chen, Chen, Yuan-Tsong, Chern, Yijuang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774278/
https://www.ncbi.nlm.nih.gov/pubmed/19924295
http://dx.doi.org/10.1371/journal.pone.0007868