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LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells
BACKGROUND: Expression of kappa gene is under the control of distinct cis-regulatory elements, including the kappa intron enhancer (iE(κ)) and the kappa 3' enhancer (3'E(κ)). The active enhancers and expression of immunoglobulin is generally considered to be restricted to B lymphocytes. Ho...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774294/ https://www.ncbi.nlm.nih.gov/pubmed/19860880 http://dx.doi.org/10.1186/1476-4598-8-92 |