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Novel association of APC with intermediate filaments identified using a new versatile APC antibody

BACKGROUND: As a key player in suppression of colon tumorigenesis, Adenomatous Polyposis Coli (APC) has been widely studied to determine its cellular functions. However, inconsistencies of commercially available APC antibodies have limited the exploration of APC function. APC is implicated in spindl...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Azuma, Yoshiaki, Friedman, David B, Coffey, Robert J, Neufeld, Kristi L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774295/
https://www.ncbi.nlm.nih.gov/pubmed/19845967
http://dx.doi.org/10.1186/1471-2121-10-75