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A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays

BACKGROUND: Regulation of gene expression is essential for normal development and cellular growth. Transcriptional events are tightly controlled both spatially and temporally by specific DNA-protein interactions. In this study we finely map the genome-wide targets of the CREB protein across all know...

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Detalles Bibliográficos
Autores principales: Hartzell, Danette D, Trinklein, Nathan D, Mendez, Jacqui, Murphy, Nancy, Aldred, Shelley F, Wood, Keith, Urh, Marjeta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774331/
https://www.ncbi.nlm.nih.gov/pubmed/19860899
http://dx.doi.org/10.1186/1471-2164-10-497