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Cellular Assays for High-Throughput Screening for Modulators of Trk Receptor Tyrosine Kinases
Trk receptor tyrosine kinases are required for signal transduction initiated by neurotrophins leading to cell proliferation, differentiation, survival and death. Alterations in Trk kinase activity have been linked to various diseases. To address the need for cell-based assays for screening and study...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774616/ https://www.ncbi.nlm.nih.gov/pubmed/20161825 http://dx.doi.org/10.2174/1875397300801010027 |