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Modulation of Protein Kinase CK2 Activity by Fragments of CFTR Encompassing F508 May Reflect Functional Links with Cystic Fibrosis Pathogenesis

[Image: see text] Deletion of F508 in the first nucleotide binding domain (NBD1) of cystic fibrosis transmembrane conductance regulator protein (CFTR) is the commonest cause of cystic fibrosis (CF). Functional interactions between CFTR and CK2, a highly pleiotropic protein kinase, have been recently...

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Detalles Bibliográficos
Autores principales: Pagano, Mario A., Arrigoni, Giorgio, Marin, Oriano, Sarno, Stefania, Meggio, Flavio, Treharne, Kate J., Mehta, Anil, Pinna, Lorenzo A.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774623/
https://www.ncbi.nlm.nih.gov/pubmed/18597485
http://dx.doi.org/10.1021/bi800316z