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Cellular Ser/Thr-Kinase Assays Using Generic Peptide Substrates

High-throughput cellular profiling has successfully stimulated early drug discovery pipelines by facilitating targeted as well as opportunistic lead finding, hit annotation and SAR analysis. While automation-friendly universal assay formats exist to address most established drug target classes like...

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Detalles Bibliográficos
Autores principales: Adams, Deanna G, Wang, Yu, Mak, Puiying A, Chyba, Jason, Shalizi, Orzala, Matzen, Jason, Anderson, Paul, Smith, Tim R, Garcia, Michael, Welch, Genevieve L, Claret, Emmanuel J, Fink, Michel, Orth, Anthony P, Caldwell, Jeremy S, Brinker, Achim
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774688/
https://www.ncbi.nlm.nih.gov/pubmed/20161828
http://dx.doi.org/10.2174/1875397300801010054