Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells

Mitochondria are found in all eukaryotic cells and contain their own genome (mtDNA). Unlike the nuclear genome which is derived from both the egg and sperm at fertilization, the mtDNA in the embryo are derived almost exclusively from the egg, i.e. is of maternal origin. Mutations in mtDNA contribute...

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Detalles Bibliográficos
Autores principales: Tachibana, Masahito, Sparman, Michelle, Sritanaudomchai, Hathaitip, Ma, Hong, Clepper, Lisa, Woodward, Joy, Li, Ying, Ramsey, Cathy, Kolotushkina, Olena, Mitalipov, Shoukhrat
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774772/
https://www.ncbi.nlm.nih.gov/pubmed/19710649
http://dx.doi.org/10.1038/nature08368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774772/
https://www.ncbi.nlm.nih.gov/pubmed/19710649
http://dx.doi.org/10.1038/nature08368

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