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Generation and Characterization of Fmr1 Knockout Zebrafish

Fragile X syndrome (FXS) is one of the most common known causes of inherited mental retardation. The gene mutated in FXS is named FMR1, and is well conserved from human to Drosophila. In order to generate a genetic tool to study FMR1 function during vertebrate development, we generated two mutant al...

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Detalles Bibliográficos
Autores principales: den Broeder, Marjo J., van der Linde, Herma, Brouwer, Judith R., Oostra, Ben A., Willemsen, Rob, Ketting, René F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774943/
https://www.ncbi.nlm.nih.gov/pubmed/19936290
http://dx.doi.org/10.1371/journal.pone.0007910