Generation and Initial Characterization of FDD Knock In Mice

BACKGROUND: Mutations in the integral membrane protein 2B [1], also known as BRI(2) [2], a type II trans-membrane domain protein cause two autosomal dominant neurodegenerative diseases, Familial British and Danish Dementia [3]. In these conditions, accumulation of a C-terminal peptide (ABri and ADan...

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Detalles Bibliográficos
Autores principales: Giliberto, Luca, Matsuda, Shuji, Vidal, Ruben, D'Adamio, Luciano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774945/
https://www.ncbi.nlm.nih.gov/pubmed/19924302
http://dx.doi.org/10.1371/journal.pone.0007900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774945/
https://www.ncbi.nlm.nih.gov/pubmed/19924302
http://dx.doi.org/10.1371/journal.pone.0007900

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