H-Ras Expression in Immortalized Keratinocytes Produces an Invasive Epithelium in Cultured Skin Equivalents

BACKGROUND: Ras proteins affect both proliferation and expression of collagen-degrading enzymes, two important processes in cancer progression. Normal skin architecture is dependent both on the coordinated proliferation and stratification of keratinocytes, as well as the maintenance of a collagen-ri...

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Detalles Bibliográficos
Autores principales: Vaughan, Melville B., Ramirez, Ruben D., Andrews, Capri M., Wright, Woodring E., Shay, Jerry W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774948/
https://www.ncbi.nlm.nih.gov/pubmed/19936293
http://dx.doi.org/10.1371/journal.pone.0007908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774948/
https://www.ncbi.nlm.nih.gov/pubmed/19936293
http://dx.doi.org/10.1371/journal.pone.0007908

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