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Dynamic Allostery in the Methionine Repressor Revealed by Force Distribution Analysis

Many fundamental cellular processes such as gene expression are tightly regulated by protein allostery. Allosteric signal propagation from the regulatory to the active site requires long-range communication, the molecular mechanism of which remains a matter of debate. A classical example for long-ra...

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Detalles Bibliográficos
Autores principales: Stacklies, Wolfram, Xia, Fei, Gräter, Frauke
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775130/
https://www.ncbi.nlm.nih.gov/pubmed/19936294
http://dx.doi.org/10.1371/journal.pcbi.1000574